Wordlwide , allergic diseases are the largest group of non communicable diseases . The prevalence of atopic eczema is % 25 of infants. Starting probiotics in early pregnancy and continue it throughout in pregnancy and for 6 months postpartum while breast feeding , only given to the mother causes fetal production of IGE antibodies . A probiotic intervention from early pregnancy , it found to protect against sensitization, may also reduce the prevalence of clinically important eczema